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Exosome For Professional Use

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EXO Balm

Exosome Post-Care Optimizing Balm

Exosomes and intensive hydrators to optimize treatment results and reduce inflammation and downtime.

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EXO Balm

Post Treatment  &  Home-Care Use

Our clinically proven intensive dual-action post-care optimizing balm is designed to quickly absorb into the skin delivering the concentrated power of exosomes and intensive hydrators to optimize treatment results and reduce downtime.

Discalimer:
United States customers only.
BENEV Exosome Products are post care “topical use” cosmetic solutions. The isolated and purified exosomes in both products have been accepted by the PCPC, and International Cosmetic Ingredient Nomenclature Committee (INC), and the name ‘Human Adipose Stromal Cell Exosomes’ was given and published in the International Cosmetic Ingredient Dictionary and Handbook, known as INCI book. There are at this time no other cosmetic INCI name(s) assigned to exosome products in the market prior to this accomplishment. These products are not drug products. They are not intended to prevent, treat or cure diseases or medical conditions. They are not intended to be injected or delivered intravenously.

ADVANCED INGREDIENTS

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  • Lyophilized Exosome

  • Growth Factors & Peptides

  • Amino acids & Humectants

  • Vitamins & Minerals

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Exosome Capsule  | 20 MG

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EXOSOME
Human Adipose Stromal Cell Exosomes
Rose Stem Cell Exosome

sh-Polypeptide-76
Pentapeptide-4
Hexapeptide-8
Nonapeptide-1

GROWTH FACTORS + PEPTIDES
sh-Oligopeptide-1
sh-Oligopeptide-2
sh-Polypeptide-1
sh-Polypeptide-3

Palmitoy Pentapeptide-7
Palmitoyl Tetrapeptide-7

Palmitoyl Tripeptide-1

AMINO ACIDS
Lysine
Methionine
Glutamic Acid
Histidine

Serine
Trytophan
Glutathione

HUMECTANTS
Sodium Hyaluronate
Trehalose
Mannitol

VITAMINS & MINERALS
Coenzyme A
Disodium Flavine Adenine Dinucleotide (FAD)
Nicotinamide Adenine Dinucleotide (NAD)
Biotin
Ascorbic Acid
Cyanocobalamin
Magnesium Sulfate
Potassium Chlorine

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Recommended For

  • Inflamed skin or skin in need of soothing

  • ​Thin & sensitive skin due to environmental causes or frequent procedure

  • Skin in need of strengthening the skin barrier

  • Skin prone to pigmentation

  • Skin in need of skin texture improvement

REAL RESULTS

B&A

PROFESSIONAL VS. HOME CARE

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Directions

Exosome Capsule

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Post-Care Optimizing Balm

Step 1: Combine Exosome Capsule (No.1) into Post-Care Optimizing Balm (No.2). Mix thoroughly with the enclosed spatula.
Step 2: Cleanse skin thoroughly and dry it completely.
Step 3: Apply EXO Balm to the skin in the morning and evening as needed. 
Step 4: Follow with sun protection as specified by your Medical Provider. 

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Protocol

STEP 1

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Cleanse

Wash face with BENEV Cleanser and warm water.

PATENTS

Application No. (filing date)
Patent Number
Read Here
Title of Invention
Abstract of Invention
Granted date
Issue Date
16/727,739 (12/26/2019)
US 11,612,621 B2
https://www.dropbox.com/s/orli876hvs8ypmm/1.%20Patent%20Letters_US%2011%2C337%2C419%20B2%20%28Lyophilization%29.pdf?dl=0
Use of Composition Comprising Exosome Derived From Adipose-derived Stem Cell as Effective Ingredient in Ameliorating Dermatitis
The present invention provides a composition for preventing, ameliorating, alleviating or treating dermatitis comprising exosomes derived from adipose-derived stem cells as an active ingredient. The composition of the present invention is able to act against dermatitis-inducing multiple cytokine targets, and thus be widely applied against dermatitis caused by various factors and effectively suppress and alleviate dermatitis.
02/08/2023
03/28/2023
17/171,399 (02/09/2021)
US 11,534,392 B2
https://www.dropbox.com/s/3rt33ums8mexp32/2.%20Patent%20Letters_US%2011%2C446%2C333%20B2%20%28pruritus%29.pdf?dl=0
Cosmetic Composition Comprising Exosomes Derived From Galactomyces as Active Ingredient
A cosmetic composition including exosomes derived from Galactomyces as an active ingredient is provided for skin regeneration, skin elasticity improvement or skin wrinkle reduction. The cosmetic composition has excellent effects on skin regeneration, skin elasticity improvement and/or skin wrinkle reduction.
11/02/2001
12/27/2022
16/913,624 (06/262020)
US 11,529,306 B2
https://www.dropbox.com/s/j13eyf8adxk6kzn/3.%20Patent%20Letters_US%2011%2C529%2C370%20B2%20%28Skin%20barrier%29.pdf?dl=0
Lyophilized Formulation of Stem-cell Derived Exosomes and Anti-inflammatory Composition Including The Same as Active Ingredient
The lyophilized formulation of stem cell-derived exosomes and the anti-inflammatory composition including the same as an active ingredient is able to stabilize stem cell-derived exosomes and exhibit excellent anti-inflammatory effects, and particularly, exhibit remarkable anti-inflammatory effects as compared with not-lyophilized stem cell-derived exosomes isolated and purified from conditioned media of stem cells. Therefore, the lyophilized formulation of stem cell-derived exosomes and the anti-inflammatory composition including the same as an active ingredient is able to effectively prevent, suppress, alleviate, ameliorate or treat inflammatory response or inflammatory diseases.
10/25/2022
12/20/2022
16/878,850 (05/20/2020)
US 11,529,370 B2
https://www.dropbox.com/s/r3sn73ppg941087/4.%20Patent%20Letters_US%2011%2C529%2C306%20B2%20%28Anti-inflammatory%20composition%29.pdf?dl=0
Use of Composition Comprising Stem-cell Derived Exosome as Effective Ingredient in Strengthening Skin Barrier and Improving Skin Barrier
A composition for strengthening skin barrier or improving skin barrier function is able to improve objective indicators related to the protection of skin barrier, the strengthening of skin barrier, and/or the improvement of skin barrier function. The composition exhibits the effects of increasing the amount of ceramides, dihydroceramides and sphingoid bases, increasing the activities of enzymes that are involved in the synthesis thereof, and decreasing the activities of enzymes that are involved in the degradation thereof. In addition, the composition is able to restore skin barrier function by reducing TSLP, IL-4, and IL-13 which are closely associated with skin barrier damage, and thus interrupting a vicious circle in which the lipids and proteins contributing to skin barrier decrease.
10/31/2022
12/20/2022
16/727,173 (12/26/2019)
US 11,446,333 B2
https://www.dropbox.com/s/lwg5xkdy54fx86k/5.%20Patent%20Letters_US%2011%2C534%2C392%20B2%20%28Galactomyces%29.pdf?dl=0
Use of Composition Comprising Stem-cell Derived Exosome as Effective Ingredient for Suppression or Alleviation of Pruritus
The present invention provides a composition for preventing, suppressing, alleviating, ameliorating or treating pruritus comprising stem cell-derived exosomes as an active ingredient. The composition of the present invention is able to act against pruritus-inducing multiple cytokine targets, for example, IL-4, IL-31 and TSLP, and thus is able to be widely applied against pruritus caused by various factors and is able to effectively suppress and alleviate pruritus. In addition, when the composition of the present invention is applied directly to human skin, it is able to remarkably ameliorate pruritus-associated clinical scores, erythema and the like. Thus, the composition of the present invention is able to be used as a pharmaceutical composition, a skin external preparation and a cosmetic composition for preventing, suppressing, alleviating, ameliorating or treating pruritus.
08/10/2022
09/20/2022
16/913,258 (06/26/2020)
US 11,337,419 B2
https://www.dropbox.com/s/ogd6suhos5hmecx/6.%20Publication_US%202020-0121723%20A1%20%28Atopic%20dermatitis%29_granted.pdf?dl=0
Method for Lyophilizing Exosome
A method of lyophilizing exosomes using a cryoprotectant comprising methionine, mannitol and trehalose is disclosed. The lyophilized exosome product shows a good appearance which maintains a porous sponge shape without forming ice crystals. In addition, the lyophilized exosome product can be applied to a pharmaceutical composition, a skin external preparation and a cosmetic composition. For example, the lyophilized exosome product can be used as a solution obtained by simply mixing it with a diluent.
05/24/2022
05/24/2022
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